Naturopathic Approach to Functional Dyspepsia:

A Case Report

Published in Integrative Medicine: Clinician's Journal (IMCJ)

Note: full text only available with subscription to IMCJ


Functional dyspepsia is a common presenting concern that includes symptoms such as gastrointestinal reflux, post-prandial bloating, and abdominal pain. Aside from mainstay conventional therapies such as proton-pump inhibitors (PPIs) and antacid tablets that seek to manage symptoms, naturopathic therapies can similarly offer symptom relief and simultaneously address factors underlying functional digestive disturbances. In this case, a 25-year-old female and first-year graduate student presented with abdominal bloating, epigastric pain, flatulence, eructations, reflux, and straining with stool. Onset of symptoms occurred after her recent transition to graduate school, which resulted in a more stressful and rigorous workload, time-pressured eating habits, and a dearth of whole food consumption. Physical exam findings were unremarkable except for moderate epigastric pain, hyperactive bowel sounds, and a geographic tongue. While she met all of the Rome IV criteria for functional dyspepsia, clinical findings did not warrant referral for endoscopy to rule out structural/organic causes of disease. As a result, therapeutic interventions consisted of an elimination diet, the use of apple cider vinegar (ACV) and L-glutamine powder in addition to a compounded homeopathic formula containing UNDA #4 and Nux vomica. Within one week, the patient reported significant improvement in presenting concerns, and within one month had denied the presence of every presenting symptom except for straining with stool. This case demonstrates that a naturopathic approach to functional dyspepsia can offer significant symptom relief as soon as one week after treatment, and that an effective treatment plan can be offered to patients in one visit lasting no longer than 60 minutes. Furthermore, compliant patients can experience a significant improvement in overall gastrointestinal function as early as one month after treatment initiation.





1. Longstreth GF, Lacy BE. Approach to the adult with dyspepsia. In: UpToDate. Waltham, Mass. UpToDate; 2019. Accessed March 22, 2020.

2. Moses, S. Dyspepsia. Family Practice Notebook. Published March 9, 2020. Accessed March 22, 2020.

3. Kahrlias PJ. Clinical manifestations and diagnosis of gastroesophageal reflux in adults. In: UpToDate. Waltham, Mass.: UpToDate; 2020. Accessed March 22, 2020.

4. Moses, S. Dyspepsia. Family Practice Notebook. Published March 9, 2020. Accessed March 22, 2020

5. Blaser MJ. Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues. New York: Picador; 2015

6. Moses, S. Helicobacter Pylori. Family Practice Notebook. Published March 9, 2020. Accessed March 22, 2020

7. Wood RA. Diagnostic elimination diets and oral food provocation. Chem Immunol Allergy. 2015;101:87-95. Doi: 10.1159/000371680.

8. Aucoin M., Lalonde-Parsi MJ., and Cooley K. Mindfulness-Based Therapies in the Treatment of Functional

Gastrointestinal Disorders: A Meta-Analysis. Evid Based Complement Alternat Med. 2014. Doi: 10.1155/2014/140724

9. Dimidi E, Cox SR, Rossi M, et. al. Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease. Nutrients. 2019; 11(8): 1806. Doi:10.3390/nu11081806

10. Nielsen ES, Garnas E, Jensen KJ, et al. Lacto-fermented sauerkraut improves symptoms in IBS patients independent of product pasteurization—a pilot study. Food Funct. 2018;9(10):5323-5335. Doi:10.1039/c8fo00968f.

11. Kines K, Krupczak T. Nutritional Interventions for Gastroesophageal Reflux, Irritable Bowel Syndrome, and Hypochlorhydria: A Case Report. Integr Med (Encinitas). 2016;15(4):49-53.

12. Ghayur MN, Gilani AH. Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders. Dig. Dis. Sci. 2005;50:1889–1897. doi: 10.1007/s10620-005-2957-2.

13. Wu KL, Rayner CK, Chuah SK, et. al. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol. 2008;20:436–440. doi: 10.1097/MEG.0b013e3282f4b224

14. Kim MH, Kim H. The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases. Int J Mol Sci. 2017;18(5):1051. Doi: 10.3390/ijms18051051

15. Gueniot G. Clinical Protocols Supporting Nature Cure and Biotherapeutic Drainage Therapy. Seroyal; 2014.

16. Merck & CO. Inc. The Merck Manual: Sixth Edition. New Jersey: Rahway. 1934

17. Frans Vermeulen. Synoptic Reference One. United Kingdom. 2011.